What Increases The Risk Of Calciphylaxis?

Calciphylaxis is an uncommon but serious disease where calcium builds up in the small blood vessels of skin and fat tissues. Often times, calciphylaxis occurs in patients who have had a kidney transplant, who have kidney failure and are on dialysis, or who have end-stage renal disease. This disease manifests in the form of skin lesions on areas of the body that contain a higher content of fat, such as the lower limbs, abdomen, buttocks, and breasts. These skin lesions do not heal and become painful nodules and ulcers. Other symptoms that occur in patients who have calciphylaxis include weakness, depression, fatigue, body aches, and cramps.