How To Treat Familial Amyloid Polyneuropathy

Familial amyloid polyneuropathy (FAP), also called transthyretin, is a rare genetic disease that progresses over time. The condition occurs when a person has mutations in their TTR gene. Quite a few different mutations have been recorded to the TTR gene, which means symptoms for individuals with familial amyloid polyneuropathy will vary widely. Some individuals with gene mutations may not even show any symptoms. The TTR gene is responsible for creating a protein that transports thyroxine and vitamin A through the body. With familial amyloid polyneuropathy, a mutated protein causes amyloid deposits to form in different tissues. Typically, the eyes, kidneys, heart, and nerves are affected.