Guide To The Causes And Treatment Of Sideroblastic Anemia

Transfusions

For sideroblastic anemia patients who do not effectively respond to other treatments, blood transfusion therapy is the next best option. Transfusion therapy is only used in cases where the individual has sideroblastic anemia that is problematic, symptomatic, and severe. Because the bone marrow of sideroblastic anemia patients cannot make adequate amounts of healthy red blood cells, a transfusion of healthy blood can help with anemia symptoms and poor blood oxygen levels. Blood transfusions require an eligible donor with a compatible blood type free of any disease or infections. Transfusion therapy is used conservatively and has limitations because of the potential dangers it poses in the form of iron toxicity and overload. Individuals who do not receive transfusions as part of their sideroblastic anemia treatment still often struggle with iron overload. Chelating agents and other measures to mediate high iron levels are often administered along with regular blood transfusions to try and prevent complications such as organ damage.