Symptoms Of Aplastic Anemia

Prolonged Bleeding

Individuals affected by aplastic anemia commonly experience the symptom of prolonged bleeding due to the effects of their blood and bone marrow condition. When healthy individuals experience bleeding inside or outside of the body, the coagulation cascade is triggered. The coagulation cascade is a combination of processes involving specialized proteins and platelets in the blood that form a blood clot to stop bleeding. Aplastic anemia patients have bone marrow that does not produce new blood cells as quickly as old blood cells are dying off. These blood cells include the red blood cells that carry oxygen, the white blood cells of the immune system, and platelets. The main component of blood vital for the coagulation cascade are platelets. Platelets are tiny blood cells that stick together to form a blood clot. A blood clot is unable to develop if there are not enough platelets present in an individual's blood. The bone marrow is responsible for the production of platelets. Individuals with aplastic anemia have platelets that die at the end of their life cycle and are not adequately replaced. This malfunction causes the patient to experience prolonged bleeding when a blood vessel becomes injured due to the body's inability to form blood clots properly.

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