Signs Of Paroxysmal Nocturnal Hemoglobinuria

Abdominal Or Back Pain

There are two main reasons for having abdominal or back pain when diagnosed with paroxysmal nocturnal hemoglobinuria. The first is due to the low levels of nitric oxide, which is also responsible for ensuring the muscles in your small intestine are working smoothly. As the levels of hemoglobin rise and the available nitric oxide lower, these muscles become more prone to spasms and decreased functioning. This can occur in your intestine and as far up as your esophagus.

The other reason you may experience pain is due to your kidneys malfunctioning. The hemolysis in your body, the break down of red blood cells, combined with potential clots as well as the medication and treatments being used are all filtered through the kidneys. This can lead to kidney damage ranging from mild to severe enough to require dialysis. Kidney pain is frequently described as being in your lower back and possibly your abdomen.

Continue to learn more about bruising and bleeding at symptoms of paroxysmal nocturnal hemoglobinuria.