Causes Of Laryngeal Cancer To Watch For

Genetic Conditions

Genetic conditions leading to laryngeal cancer are hereditary and the most difficult risk factors to avoid. Two such conditions are Fanconi anemia (FA) and dyskeratosis congenita (DC or DKC). FA stops the production of new red blood cells within your bone marrow, which greatly enhances the risk of leukemia and cancers of the mouth and throat. Fanconi anemia affects both men and women of all racial and ethnic groups, although Ashkenazi Jews and Afrikaners are more likely to have the blood disorder or to carry the mutation that causes it. Roughly one in 130,000 babies born annually in the United States has this condition. Dyskeratosis congenita is a similar bone marrow failure syndrome that often presents with abnormal fingernail and toenail growth as well as skin rashes. This inherited gene defect is associated with a higher than normal risk of throat cancer. Androgen therapy, the use of human-made hormones to stimulate the production of red blood cells and platelets, appears to mitigate the most common health outcomes of dyskeratosis congenita and Fanconi anemia.

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