Most Common Types Of Cancer Found In Li-Fraumeni Syndrome

Osteosarcoma

Osteosarcoma is a form of malignancy that develops in the bone-forming cells of the body. The long bones are most affected by osteosarcoma, including the long bones in the arms and legs. Individuals who have Li-Fraumeni syndrome precipitated osteosarcoma experience symptoms that include joint pain, bone swelling, joint swelling, bone pain, and bone injury or fracture with little to no impact. Osteosarcoma can metastasize to other tissues in the affected individual's body, which makes treatment challenging. Osteosarcoma is diagnosed with the use of x-rays, MRI scans, CT scans, bone scan, bone needle biopsy, and surgical bone biopsy. This type of tumor is treated with radiation therapy, chemotherapy, and surgery. Many patients undergo chemotherapy before having surgery to remove their osteosarcoma. Surgical procedures to remove osteosarcoma may involve the amputation of the limb, installation of a metal implant, or installation of an allograft to retain the appearance and functionality of the limb.

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