Signs And Symptoms Of Large Cell Carcinoma

Paraneoplastic Syndrome

Paraneoplastic syndrome is most commonly found in lung cancer cases, but the exact pathogenesis of this cluster of symptoms is still unknown. Scientists speculate this syndrome arises as a result of substances secreted by the tumors in the lungs or by the antibodies having cross-reactions with other tissues once they have been sent out to fight the tumors. An estimated twenty percent of large cell carcinoma patients will experience this syndrome during their illness. Symptoms include night sweats, cachexia, anorexia, and fever. Skin problems might also arise, such as flushing, itching, keratoses, and even herpes zoster, which is better known as shingles. The endocrine, gastrointestinal, and neurological systems in the body are also affected, leading to diversity in symptoms.

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