Major Types Of Non-Hodgkin Lymphoma And Their Signs

Mantle Cell Lymphoma

Mantle cell lymphoma (MCL) is a rare type of non-Hodgkin lymphoma that comprises approximately fifteen thousand patients in the United States. It emerges at the outer mantle of the lymph node follicle due to the abnormal transformation of B-cells. The cells can enter the lymphatic or blood systems and spread to other parts of the body. It occurs mostly to individuals over sixty and is more predominant in men than women.

The signs and symptoms of MCL include fever, fatigue, enlargement of the liver, and weight loss. The cause of mantle cell lymphoma has not been established, but most cases have been related to a genetic abnormality known as translocation.

Due to the painless symptoms, most cases are diagnosed in advanced stages. The diagnosis is made by the examination of needle aspiration of the lymph nodes or biopsies of the bone marrow. There is no cure for MCL, but treatment options include chemotherapy, radiotherapy, and surgery.

Continue reading to learn about the final type of non-Hodgkin lymphoma.