Guide To The Causes And Complications Of Pituitary Tumors

Genetic Mutations Later In Life

Some individuals develop tumors in their pituitary glands as a result of genetic mutations acquired later in their life, which can be due to a number of factors. The first factor known to play a role in pituitary tumorigenesis is an individual's hormone fluctuations throughout life. Genetic mutations that cause a pituitary tumor to develop can be caused by a post-menopausal phenomenon, such as post-menopausal periods. Patients who utilize hormone replacement therapy are also more likely to develop a mutation that causes the development of a pituitary tumor. For unknown reasons, individuals who gave birth at a young age are at an increased risk of developing a tumor in their pituitary gland later on in their life. A previous history of personal parathyroid, thyroid, colorectal, and adrenal tumors also causes an individual to be at a higher risk of developing tumors in the pituitary gland. In a small number of patients affected by pituitary tumors, a positive correlation was made with having had a twin pregnancy. A previous head injury or head trauma has predisposed some individuals to mutations that cause the development of a pituitary tumor.

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