Causes And Risk Factors Linked To Avascular Necrosis

Sickle Cell Anemia

Sickle cell anemia is another genetic condition that is a major risk factor for the development of avascular necrosis. For patients with sickle cell anemia, the red blood cells are an atypical shape, and they break down faster than they should. This leads to anemia (low red blood cell count) and can cause fatigue, frequent infections, shortness of breath, and episodes of severe pain requiring hospitalization. Some patients may develop jaundice, and the condition damages the liver, spleen, and other organs. As children, sickle cell patients may have delayed growth and development. Patients with this condition are known to have a low bone density, and this in itself can elevate their risk of avascular necrosis. The sickle shape of these patient's blood cells also makes it more difficult for blood to flow to the bones effectively, further elevating the risk of avascular necrosis.

Learn more about what causes or at least increases the risk of avascular necrosis now.