Causes, Risk Factors, And Complications Of Progressive Supranuclear Palsy

Difficulty Sleeping

Problems with initiating and maintaining a restful sleep are common among individuals with neurodegenerative disorders, like Alzheimer's disease, Parkinson's disease, and progressive supranuclear palsy. The problems with sleep in affected individuals have an association with the neuroanatomical parts of the brain affected by the degeneration that occurs in progressive supranuclear palsy being the same parts of the brain that are responsible for housing the individual's sleep/wake regulation system. On average, it can take an individual with progressive supranuclear palsy over an hour to fall asleep compared to between ten and twenty minutes for a healthy individual. Progressive supranuclear palsy patients are known to wake during the night more frequently than healthy individuals. Comorbidities like sleep apnea and restless leg syndrome are also common in individuals who have progressive supranuclear palsy, which can also contribute to difficulties with sleep.

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