What Causes Sialorrhea?

Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurological condition that causes a loss of muscle control. The condition usually begins in the hands, feet, arms, or legs, and patients may fall or have difficulty walking. Muscle cramps and twitching could occur in the tongue, arms, and shoulders, and changes in cognition and behavior might be observed. Patients may slur their speech or have trouble swallowing, and they could cry or laugh at inappropriate times. As the condition advances, patients often begin to have trouble breathing, chewing, and speaking. ALS cannot be cured, and it eventually progresses to the point where it is fatal. Treatment methods focus on slowing the progression of the disease, managing symptoms, and improving quality of life. Patients may benefit from riluzole, a medication that can extend lifespan, and edaravone, a drug that reduces the decline of daily functioning. Physical, occupational, and speech therapies are often recommended, and patients may need to have mechanical ventilation to assist with breathing.

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