Common Risk Factors And Causes Of Cystitis

Certain Medications

An individual who has taken certain medications can develop cystitis as a result of their treatment. Drugs used in chemotherapy have been known to cause the onset of cystitis in affected individuals. These are potent drugs that enter the body, create waste products, and are broken down before the kidneys filter them from the blood. Just like anything else, what goes in the body must come out. These drug components and the waste products they produce are filtered into the individual's urine, which sits in the bladder until it is ready to be emptied. These substances cause irritation and even damage to the cells lining the bladder in this process of bodily elimination. Drugs commonly implicated in this mechanism are ifosfamide and cyclophosphamide. Drugs that cause an impairment of the healthy bladder emptying process and flow of urine can increase the risk of developing cystitis. Immunosuppressive medications may be used in individuals with autoimmune disorders to help minimize the symptoms of their disorder, but increase their vulnerability to pathogens that cause bladder infections. Immunosuppressant drugs are also used in individuals who have received an organ transplant to prevent donor organ rejection. An impaired immune system due to medication can increase the risk of cystitis.

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