Significant Risk Factors Of Dupuytren's Contracture

Epilepsy Medication

It has been known for nearly half a century that epilepsy patients tend to have a higher incidence of Dupuytren's contracture than the average population. After investigation into this prevalence, the researchers came to the conclusion that epilepsy medication is the main cause. Prolonged administration of anticonvulsants can lead patients to develop Dupuytren's contracture. In the original study of epilepsy patients, fifty-six percent also went on to develop Dupuytren's contracture. The majority of the lesions were symmetrical and bilateral, and they tended to be associated with plantar nodules and knuckle pads. At the same time, the researchers didn't develop any known correlation between Dupuytren's contracture and frozen shoulder. During the study, patients appeared to have a heightened chance of Dupuytren's contracture regardless of what kind of epilepsy they had. At the time of the study, anticonvulsants other than phenobarbitone had only been introduced recently. The study indicated these anticonvulsants also increased a patient's chances of developing Dupuytren's contracture in addition to phenobarbitone.

Reveal another risk factor for Dupuytren's contracture now.