Signs Of Paget's Disease

Bone Fractures

Normal bone is strong because old bone is broken down and replaced with new, healthy bone, a process called remodeling. Paget's disease causes a derangement of this normal process and bone is broken down too quickly. Instead of being replaced with healthy bone, the replacement bone is misshapen, weak, and easily broken. When the bones are weak, bone fractures can occur with normal use. Compression fractures of the vertebra may occur, and these may cause pain in the back or neck. Suggested treatments for bone fractures caused by Paget's disease are designed to help increase bone strength, inhibit the breakdown of bone, and also slow the progression of other Paget's disease symptoms, such as hearing loss.

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