Serious Symptoms Of Chronic Inflammatory Demyelinating Polyneuropathy (CIDP)

Progressive Limb Weakness

Generally, motor system dysfunction due to the weakness of the muscles is more prevalent in individuals affected by chronic inflammatory demyelinating polyneuropathy than sensory nerve malfunction. The most common pattern of progressive weakness of the limbs occurs in a patient's legs and arms in a symmetric fashion. In the earlier stages of CIDP, the patient may not exhibit muscle wasting or atrophy. However, muscle tone may appear to be decreased in individuals in the later stages of the illness. Muscle weakness occurs in individuals who have CIDP because the immune system destroys the myelin sheathing that covers the nerves responsible for transmitting impulses that tell the muscles to contract. Muscle weakness describes the inability to move a muscle when the greatest effort is made to do so. This malfunction occurs when damage has been done to the nerve sheathing, and the impulses that trigger the contraction of the muscle cannot reach the muscle tissue itself. Limb weakness in affected individuals often presents as abnormalities in their gait.

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