How To Spot Fabry Disease

Joint Pain

Joint pain is another common type of pain associated with Fabry disease. Many patients with Fabry disease don't experience pain throughout all of the joints, as is common with other autoimmune and rheumatoid diseases. Instead, the pain most often presents as a chronic, burning, tingling, and nagging pain throughout the feet and hands. The pain starts during an individual's childhood and continues throughout their adulthood. When GL-3 accumulates in the blood vessel walls in the skin tissue, the person's nerve fibers degenerate. The disease causes individuals to lose some of their small sensory neurons, which some experts believe might contribute to the pain of Fabry disease. Pain in the hands and feet is one of the most common aspects of Fabry disease. This is the symptom that tends to set Fabry disease apart from other disorders with similar symptoms.