Symptoms Of Fraser Syndrome To Watch For

Fraser syndrome is a rare type of genetic disorder generally characterized by fused eyelids, fusing of the skin found between the toes and fingers, and abnormalities found in the urinary tract. Symptoms and signs tend to show up early in the development. They may also include respiratory tract abnormalities, failure of the kidneys to develop properly, abnormalities of the ear and nose, a cleft lip, skeletal abnormalities, and intellectual disability. In particularly severe cases, Fraser syndrome might be fatal before a child is born or shortly after their birth. When an individual is less severely affected, they can live into childhood or sometimes even adulthood. Fraser syndrome's primary cause is mutations in three genes.

These are the main symptoms of Fraser syndrome.

Complete Fusion Of Eyelids

Complete fusion of the eyelids is one of the most characteristic signs of Fraser syndrome. This condition, otherwise known as cryptophthalmos, will generally cause eyes to appear as though they have been completely covered in skin. The eyes themselves will usually have some malformation. It's common for the eyes to be too small for the face, or for the eyes to be missing entirely. In addition, the tear ducts might be malformed or fail to develop at all. There is sometimes an increased distance between the patient's eyes. All of these combined symptoms tend to lead to vision loss if the patient had the capacity for vision in the first place. It's common for Fraser syndrome patients to be completely blind.

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