Symptoms Of Situs Inversis

Primary Ciliary Dyskinesia

Also known as PCD or immotile ciliary syndrome, primary ciliary dyskinesia is a rare genetic disorder. It is ciliopathic, meaning it is a disorder of the cilia in the cells, in ciliary function, basal bodies, or those structures anchoring cilia. The defects are in the cilia's action of a wide variety of locations: those that line the respiratory tract, which includes upper and lower, middle ear, Eustachian tube, and sinuses; fallopian tubes; and sperm cells' flagella. The name immotile ciliary syndrome has fallen out of primary use as the cilia do retain some movement, but are unsynchronized or inefficient. Primary ciliary dyskinesia sometimes accompanies situs inversus, meaning it can help to diagnose the primary condition.

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