What Are The Symptoms Of Sydenham’s Chorea?

Muscle Weakness

An individual with Sydenham's chorea may develop muscle weakness, which is the inability to produce a muscle movement or muscle contraction even when exerting the greatest mental and physical efforts to do so. An affected individual's immune system launches an attack on the group A streptococcus bacteria that has become active in the brain, producing inflammation in the basal ganglia tissues. These tissues help the nerve impulse get from the brain to the spinal cord so they can reach the muscles to trigger a muscle contraction. However, this process is disrupted in Sydenham's chorea patients, stopping the full nerve impulses from reaching the muscles. Partial nerve signals that make their way to the affected muscle can cause numbness, tingling, and an inability to move the muscles when attempting to.

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