The Most Common Types Of Colon Polyps And Polyp Disorders

Gardner's Syndrome

Gardner's syndrome is an inherited condition that causes the development of cancer in the rectum and colon of an individual. It is characterized by the formation of various masses (polyps included) that are both malignant and benign. The main concern in individuals affected by Garner's syndrome is the development of colorectal cancer and other familial adenomatous polyposis or FAP-associated cancers. These cancers include those of the stomach, thyroid, liver, adrenal gland, small bowel, pancreas, central nervous system, and bile duct cancers. Other manifestations of Gardner's syndrome in affected individuals include benign growths of the bone, benign connective tissue tumors, desmoid tumors, dental abnormalities, epidermoid cysts, other skin abnormalities, and lipomas. Gardner's syndrome is caused by an autosomal dominant pattern of inheritance that carries a certain mutation in the individual's APC gene. Gardner's syndrome has no cure as of the present day, but the risk of cancer can be reduced by certain management options available for affected individuals. These include certain types of medications, high-risk screening, and prophylactic surgical procedures.

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