Treatment Options For Asterixis

Commonly known as a flapping tremor or a liver flap, asterixis is a neurological symptom. Patients with this symptom suddenly lose muscle control, and it typically affects the wrist and fingers. For example, most patients exhibit a flapping motion of the fingers when they extend their wrist. The flapping occurs on both sides of the body. Asterixis was first identified in the 1940s in patients who had liver disease. Doctors perform a series of neurological tests, checking the hands, fingers, wrists, and arms for weakness and ruling out any other conditions when diagnosing asterixis. Neurologists may also check reflexes, grip strength, coordination, and range of motion. Patients will be asked to extend their hands, flex their wrists, and spread their fingers. Typically, patients with asterixis will experience a tremor after holding this position for a few seconds. The physician may push against the patient's wrists to see if the tremor can be provoked. Occasionally, nerve conduction studies or imaging tests such as CT scans may be needed. Blood tests are often performed to look for an accumulation of certain minerals and chemicals in the bloodstream. Asterixis is associated with several different neurological conditions that can also cause confusion, sleep problems, tremors, and personality changes.Patients with asterixis may benefit from the treatments outlined below.

Liver Or Kidney Transplant

Problems with the liver and kidneys can cause asterixis. For example, patients with liver and kidney disease have impaired function in these organs, resulting in the accumulation of toxins that would normally be flushed out of the body. A disorder known as hepatic encephalopathy results in the accumulation of toxins in the brain, leading to asterixis. In addition, patients with both liver and kidney disease may experience a complication known as metabolic encephalopathy, which can also result in asterixis. Metabolic encephalopathy causes neurological misfiring due to an imbalance of vitamins and minerals that cross into the brain.

A liver or kidney transplant can correct asterixis by giving patients a healthy, functioning organ. Patients must first undergo a series of medical and psychological evaluations before being placed on the transplant list where they can await a donor organ. Transplant surgeries are carried out under general anesthesia, and recovery takes several months. Patients must take anti-rejection medications for the rest of their lives. They also require frequent follow-up appointments for monitoring.

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