How DHEA Benefits Health

Benefits Alzheimer's Disease

In Alzheimer's disease, brain cells are lost, resulting in the loss of memory with other cognitive functions. In a 2012 review, the decline in DHEA, with testosterone, is linked to the development of Alzheimer's disease. However, it is still possible other factors may be involved. DHEA's beneficial effects were tested in a 2011 study featuring female rats with Alzheimer's disease. Researchers saw an increase in brain acetylcholinesterase activity with 250 mg/kg supplementation. The decline of AChE activity is widely linked to cognitive impairment.

In a different study from 2014, DHEA was demonstrated to improve memory in male rats with vascular dementia. It is widely believed DHEA improves memory due to its inhibitory effects on cortisol, a hormone that the body produces in response to stressful events. The hormone can contribute to memory loss.

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