Differences Between Anti-Inflammatories And Pain Relievers

Effect On The Digestive System

Both anti-inflammatories and pain relievers can affect the digestive system. Anti-inflammatories commonly cause digestive symptoms including esophageal reflux, stomach irritation, and ulcers. These medications weaken the sphincter muscle between the esophagus and stomach, as well as the lining of the stomach, making both more susceptible to the acids produced in this organ. Individuals who take anti-inflammatories regularly for chronic conditions are at even greater risk of these digestive conditions. Taking a proton pump inhibitor along with the anti-inflammatories can help to reduce stomach acid and subsequent damage. Pain relievers do not typically irritate or impact the digestive system, so these can be a safer choice for those needing general pain or fever relief.