What Is Klonopin?

Potential Medication Interactions

To avoid potential medication interactions, patients should check with their doctor before using clonazepam with sleeping pills, opioids, muscle relaxers, prescription cough medicines, and any medication used to treat epilepsy, depression, or anxiety. Klonopin should not be used with other benzodiazepines. Taking it with ketoconazole, cimetidine, fluvoxamine, or itraconazole could increase the level of clonazepam in the body, and this may cause the patient to experience more severe side effects. Phenobarbital and phenytoin are known to decrease the level of clonazepam in the body, and this reduces the effectiveness of the medicine. Taking Klonopin with others that cause drowsiness, including zolpidem, certain antihistamines, and prescription cough syrups with codeine, could cause extreme sedation, and elderly patients who take both of these medicines are more likely to experience impairments in judgment, thinking, and motor skills when these medicines are used together.