Overview Of Lorazepam

Medication Interactions

Lorazepam interacts with other benzodiazepines such as alprazolam and clonazepam, as well as with opioids. Due to the risk of medication interactions, lorazepam should not be used with pain relievers or cough medicines containing codeine or hydrocodone, and it should not be used with other medicines that cause sedation. For example, it is not to be taken with some types of antidepressants, antipsychotics, or antihistamines with a sedating effect. Experts advise against using it with muscle relaxants such as carisoprodol and cyclobenzaprine, and it has strong interactions with kava, clozapine, and sodium oxybate (GHB). To avoid complications from potential medication interactions, patients should inform their medical team about all medications they take, including over-the-counter medicines, prescriptions, herbal and natural remedies, vitamins, and supplements. Doctors should check the patient's medication list for potential interactions before prescribing lorazepam, and the pharmacist should also check for interactions before the drug is dispensed.