What Is Prednisone?

Potential Medication Interactions

Prednisone can interact with barbiturates such as amobarbital and pentobarbital, and it interacts with some types of diuretics, including furosemide, bumetanide, and torsemide as well. Patients with diabetes should be aware prednisone could interfere with insulin and some of the other injectable medicines used in the treatment of this condition, and the drug also interacts with estrogens found in hormone replacement therapy and birth control pills. Prednisone is known to interact with over-the-counter pain relievers and non-steroidal anti-inflammatories, including ibuprofen and naproxen. It also interacts with the anti-inflammatories diclofenac, indomethacin, and ketoprofen. Individuals who take acetylsalicylic acid (Aspirin) or other salicylates such as choline magnesium trisalicylate should check with their healthcare team about potential interactions with prednisone.