Side Effects Of Antidepressants

Constipation

Antidepressants are one of many types of medication that can cause constipation. It's important to have a bowel movement at least once every three days, as longer periods cause the stool to become more difficult to pass. Constipation most commonly occurs with tricyclic antidepressants. Though patients are less likely to experience constipation when taking SSRIs, they do have some potential for this side effect. The reason for the problem is related to a patient's acetylcholine levels. Tricyclic antidepressants block this neurotransmitter from acting, which leads to a slowing of the muscle contractions in the digestive tract. In addition, the secretions that help lubricate feces for easier passage become drier. The best ways to decrease constipation are to eat high-fiber foods, drink lots of water, and exercise regularly.

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