Guide To The Side Effects Of Mood Stabilizers

Liver Damage

Liver damage is a relatively rare potential side effect associated with specific mood stabilizers such as carbamazepine, divalproex sodium, and topiramate. Patients may have changes in liver enzymes and liver function tests, and instances of fatal liver failure have been reported. Patients who have liver damage could experience jaundice, abdominal pain or swelling, skin itching, dark-colored urine, and pale or bloody stools. There may also be a tendency to bruise easily, and the patient might notice swelling in the legs and ankles. Individuals who take mood stabilizers may need to have liver function tests before and during treatment, and they should report any possible symptoms of liver damage to their physician immediately. In some cases, liver damage may be reversible if the mood stabilizer that causes the symptoms is stopped. Patients with pre-existing liver conditions should let their doctor know before a mood stabilizer is prescribed.

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