Side Effects Of Prednisone

Mood Changes

Many patients experience mood changes during treatment with prednisone. One patient's mood swings may vary considerably compared to another. For example, some individuals report feelings of euphoria while on the medication, and others have experienced depression, anxiety, and anger. Patients might have very quick shifts in mood during prednisone use, and mood changes often develop without provocation and for no apparent reason. Individuals who use prednisone could feel extremely sad or angry without knowing why. Prednisone is sometimes associated with more severe mental health changes, including the development of psychosis, delusions, and dementia. Mood changes are more likely to occur when prednisone is taken in higher dosages, and reducing the dose could reduce or eliminate mood swings. Patients often find their mood returns to normal once they stop taking prednisone. If mood changes are disruptive, patients should check with their doctor about switching to a different medication.

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