What Is Tramadol?

Potential Medication Interactions

Tramadol is known to interact with a variety of other medications, including anticoagulants such as warfarin and anti-fungal medicines like ketoconazole. This opioid interferes with antibiotics, including erythromycin and linezolid, and it also interacts with medication for epilepsy and migraines. In particular, tramadol has strong interactions with antidepressants, including monoamine oxidase inhibitors, tricyclic antidepressants, and selective serotonin reuptake inhibitors, and patients who take lithium or anti-anxiety medications such as sertraline or paroxetine have experienced interactions as well. Due to potential interactions, patients who take tramadol should not take any other medication containing this opioid, and they should be aware tramadol could interact with muscle relaxants and with other types of pain relievers such as oxycodone. Doctors should go over the patient's complete medication list before prescribing tramadol, and pharmacists should check for interactions before dispensing the medicine.

Learn about commonly prescribed alternatives to tramadol next.