13 Serious Problems That Hives Could Indicate
Pernicious Anemia

Pernicious anemia occurs mainly due to a vitamin B12 deficiency. The body lacks the ability to produce enough red blood cells for optimal health. Studies have shown a connection between autoimmunity in chronic hives and a lack of vitamin B12. In 2004, one such study indicated thirty-three percent of patients with chronic hives had a B12 deficiency and along with autoimmune urticaria (hives), were affected by autoimmune thyroiditis. It is not the main symptom of Pernicious anemia.