An Overview Of Stem Cell Replacement

Graft-Versus-Host Disease

Complications may arise between the donor and the patient receiving the treatment that puts the patient at an increased risk of developing graft-versus-host disease (GVHD). This disease occurs when cells taken from the donor are perceived as foreign invaders by the patient's body after receiving the treatment. Since the new immune system does not recognize these cells, it may attack them. This can result in numerous damaged organs and tissues. Symptoms of GVHD include shortness of breath, joint or muscle pain, coughing, rash, the appearance of scars on the skin, dry eyes, mouth sores, abdominal pain, dry mouth, jaundice, vomiting, nausea or diarrhea.

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